Endocrine Abstracts

Background: Type 2 diabetes mellitus (DM) is probably one of the non-communicable diseases with raised levels of glucose in the blood due to insulin efficacy. The aetiology of disease combines both genetic and lifestyle or environmental factors. (GWAS) studies have been identified CAPN10 (SNP-19), FTO (rs-9939609), MTHFR (rs1801133) and PPARG (rs1801282) genetic polymorphism with susceptibility to T2DM. The susceptibility will increase by independent risk of genetic polymorphi...